3IUC

Crystal structure of the human 70kDa heat shock protein 5 (BiP/GRP78) ATPase domain in complex with ADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa)	polymer	408	45204.0	2	UniProt (B0QZ61) Pfam (PF00012) UniProt (by SIFTS) (P11021) In PDB	Homo sapiens (human)	70kDa heat shock protein 5 (BiP), Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa), isoform CRA_a
2	A, C	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
3	A, C	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
4		water	water		18.0	399	Chemie (HOH)

Sequence modifications

A, C: 26 - 410 (UniProt: B0QZ61)

PDB	External Database	Details
Met 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Ser 10	-	expression tag
Ser 11	-	expression tag
Gly 12	-	expression tag
Val 13	-	expression tag
Asp 14	-	expression tag
Leu 15	-	expression tag
Gly 16	-	expression tag
Thr 17	-	expression tag
Glu 18	-	expression tag
Asn 19	-	expression tag
Leu 20	-	expression tag
Tyr 21	-	expression tag
Phe 22	-	expression tag
Gln 23	-	expression tag
Ser 24	-	expression tag
Met 25	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	90407.9
Non-Polymers*	Number of molecules	6
	Total formula weight	1014.7
All*	Total formula weight	91422.6

*Water molecules are not included.