3IT3
Crystal Structure Francisella tularensis histidine acid phosphatase D261A mutant complexed with substrate 3'-AMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acid phosphatase | polymer | 342 | 38558.0 | 2 | UniProt (Q2A612) | Francisella tularensis subsp. holarctica | HISTIDINE ACID PHOSPHATASE |
| 2 | C, D (A, B) | [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate | non-polymer | 347.2 | 2 | Chemie (3AM) PubChem (41211) PubChem (22803664) PubChem (256105) PubChem (1548880) PubChem (56992563) PubChem (57879890) PubChem (57879900) PubChem (92221117) PubChem (96538813) PubChem (12358318) PubChem (129093363) PubChem (171666463) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 580 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 336 (UniProt: Q2A612)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ala 261 | Asp 276 | engineered mutation |
| His 337 | - | expression tag |
| His 338 | - | expression tag |
| His 339 | - | expression tag |
| His 340 | - | expression tag |
| His 341 | - | expression tag |
| His 342 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77116.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 694.4 | |
| All* | Total formula weight | 77810.4 |
