3IRN
Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase COMPLEXED WITH NADPH AND Cycloguanil
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Bifunctional dihydrofolate reductase-thymidylate synthase | polymer | 521 | 58928.1 | 4 | UniProt (Q27793) Pfam (PF00186) Pfam (PF00303) In PDB | Trypanosoma cruzi | DHFR-TS, Dihydrofolate reductase, Thymidylate synthase |
| 2 | A, B, C, D | 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine | non-polymer | 251.7 | 4 | Chemie (1CY) | |||
| 3 | A, B, C, D | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 4 | Chemie (NDP) | |||
| 4 | A, C, D | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 5 | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 235712.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4368.4 | |
| All* | Total formula weight | 240080.9 |
