3IRM
Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase COMPLEXED WITH Cycloguanil
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Bifunctional dihydrofolate reductase-thymidylate synthase | polymer | 521 | 58928.1 | 4 | UniProt (Q27793) Pfam (PF00186) Pfam (PF00303) | Trypanosoma cruzi | DHFR-TS, Dihydrofolate reductase, Thymidylate synthase |
| 2 | E, K, Q, U (A, B, C, D) | 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine | non-polymer | 251.7 | 4 | Chemie (1CY) | |||
| 3 | F, G, L, M, R... (A, B, C, D) | PHOSPHATE ION | non-polymer | 95.0 | 8 | Chemie (PO4) | |||
| 4 | H, I, J, N, O... (A, B, C, D) | ACETATE ION | non-polymer | 59.0 | 8 | Chemie (ACT) | |||
| 5 | AA, BA, Y, Z (C, D, A, B) | water | water | 18.0 | 653 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 235712.5 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2239.0 | |
| All* | Total formula weight | 237951.5 |
