3IQU
Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (6mer)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26558.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Stratifin, Epithelial cell marker protein 1 |
| 2 | B (P) | 6-mer from RAF proto-oncogene serine/threonine-protein kinase | polymer | 6 | 759.7 | 1 | UniProt (P04049) | C-RAF, cRaf, Raf-1 | |
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D, E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | G, H (A, P) | water | water | 18.0 | 492 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27318.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 108.4 | |
| All* | Total formula weight | 27427.0 |
