3IO9
BimL12Y in complex with Mcl-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 162 | 18227.6 | 1 | UniProt (P97287) UniProt (Q07820) Pfam (PF00452) | Mus musculus (Mouse) | Bcl-2-related protein EAT/mcl1, mcl1/EAT, Bcl-2-like protein 3, Bcl2-L-3 |
| 2 | B (B) | Bcl-2-like protein 11 | polymer | 26 | 3324.7 | 1 | UniProt (O43521) Pfam (PF08945) | Homo sapiens | Bcl2-L-11, Bcl2-interacting mediator of cell death |
| 3 | C, D, E, F (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A: 171 - 208 (UniProt: P97287)
A: 209 - 327 (UniProt: Q07820)
B: 51 - 76 (UniProt: O43521)
| PDB | External Database | Details |
|---|---|---|
| Gly 166 | - | expression tag |
| Pro 167 | - | expression tag |
| Leu 168 | - | expression tag |
| Gly 169 | - | expression tag |
| Ser 170 | - | expression tag |
B: 51 - 76 (UniProt: O43521)
| PDB | External Database | Details |
|---|---|---|
| Tyr 62 | Leu 152 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21552.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 21813.9 |
