3INB

Structure of the measles virus hemagglutinin bound to the CD46 receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Hemagglutinin glycoprotein	polymer	466	51559.8	2	UniProt (P08362) Pfam (PF00423)	Measles virus strain Edmonston (viruses)
2	C, D (C, D)	Membrane cofactor protein	polymer	126	14517.6	2	UniProt (P15529) Pfam (PF00084)	Homo sapiens (human)	Trophoblast leukocyte common antigen, TLX
3	E, F, H, I, L... (A, B, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
4	G, J, K (A, B)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
5	N, O, P (A, B, C)	water	water		18.0	8	Chemie (HOH)

Sequence modifications

A, B: 179 - 617 (UniProt: P08362)

PDB	External Database	Details
Tyr 152	-	expression tag
Pro 153	-	expression tag
Tyr 154	-	expression tag
Asp 155	-	expression tag
Val 156	-	expression tag
Pro 157	-	expression tag
Asp 158	-	expression tag
Tyr 159	-	expression tag
Ala 160	-	expression tag
Gly 161	-	expression tag
Ala 162	-	expression tag
Gln 163	-	expression tag
Pro 164	-	expression tag
Ala 165	-	expression tag
Arg 166	-	expression tag
Ser 167	-	expression tag
Pro 168	-	expression tag
Gly 169	-	expression tag
Ile 170	-	expression tag
Arg 171	-	expression tag
Gly 172	-	expression tag
Leu 173	-	expression tag
Val 174	-	expression tag
Pro 175	-	expression tag
Arg 176	-	expression tag
Gly 177	-	expression tag
Ser 178	-	expression tag
Ala 331	Thr 331	engineered mutation
Thr 392	Ala 392	engineered mutation
Thr 484	Asn 484	engineered mutation
Gly 546	Ser 546	engineered mutation
Val 600	Glu 600	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	132154.6
Non-Polymers*	Number of molecules	9
	Total formula weight	1615.4
All*	Total formula weight	133770.1

*Water molecules are not included.