3IN8
Crystal Structure of the Grb2 SH2 Domain in Complex with a Flexible Ac-pTyr-Ile-Asn-NH2 Tripeptide Mimic
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Growth factor receptor-bound protein 2 | polymer | 117 | 13758.5 | 1 | UniProt (P62993) Pfam (PF00017) In PDB | Homo sapiens (human) | Adapter protein GRB2, SH2/SH3 adapter GRB2, Protein Ash |
| 2 | A | N-{(2S)-4-(methylamino)-4-oxo-2-[4-(phosphonooxy)benzyl]butanoyl}-L-isoleucyl-L-aspartamide | non-polymer | 543.5 | 1 | BIRD (PRD_000634) Chemie (FYI) | |||
| 3 | A | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 4 | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
A: 53 - 163 (UniProt: P62993)
| PDB | External Database | Details |
|---|---|---|
| His 164 | - | expression tag |
| His 165 | - | expression tag |
| His 166 | - | expression tag |
| His 167 | - | expression tag |
| His 168 | - | expression tag |
| His 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13758.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 589.5 | |
| All* | Total formula weight | 14348.1 |
