3II4
Structure of mycobacterial lipoamide dehydrogenase bound to a triazaspirodimethoxybenzoyl inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydrolipoyl dehydrogenase | polymer | 466 | 49437.0 | 2 | UniProt (P66004) Pfam (PF12831) Pfam (PF00070) Pfam (PF02852) UniProt (by SIFTS) (P9WHH9) | Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase, E3 component of alpha keto acid dehydrogenase complexes |
| 2 | C, E (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 3 | D, F (A, B) | N-[2-(2,4-dichlorophenyl)ethyl]-2-{8-[(2,4-dimethoxyphenyl)carbonyl]-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl}acetamide | non-polymer | 625.5 | 2 | Chemie (3II) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 751 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 464 (UniProt: P66004)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 98874.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2822.2 | |
| All* | Total formula weight | 101696.3 |
