3IHP

Covalent Ubiquitin-Usp5 Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Ubiquitin carboxyl-terminal hydrolase 5	polymer	854	95449.9	2	UniProt (P45974-2) Pfam (PF17807) Pfam (PF02148) Pfam (PF00443) Pfam (PF00627) UniProt (by SIFTS) (P45974) In PDB	Homo sapiens (human)	Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5, Deubiquitinating enzyme 5, Isopeptidase T
2	C, D	Ubiquitin	polymer	75	8519.8	2	UniProt (P62988) Pfam (PF00240) UniProt (by SIFTS) (P0CG48) In PDB	Homo sapiens (human)
3	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	C, D	ETHANAMINE	non-polymer		45.1	2	Chemie (NEH)
5	D	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6		water	water		18.0	32	Chemie (HOH)

Sequence modifications

A, B: 1 - 835 (UniProt: P45974-2)

PDB	External Database	Details
Met -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	207939.3
Non-Polymers*	Number of molecules	5
	Total formula weight	256.4
All*	Total formula weight	208195.8

*Water molecules are not included.