3IG6
Low molecular weigth human Urokinase type Plasminogen activator 2-[6-(3'-Aminomethyl-biphenyl-3-yloxy)-4-(3-dimethylamino-pyrrolidin-1-yl)-3,5-difluoro-pyridin-2-yloxy]-4-dimethylamino-benzoic acid complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Urokinase-type plasminogen activator | polymer | 23 | 2708.2 | 2 | UniProt (Q5SWW9) UniProt (by SIFTS) (P00749) | Homo sapiens (human) | U-plasminogen activator, uPA, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A, Urokinase-type plasminogen activator chain B |
| 2 | B, D (B, D) | Urokinase-type plasminogen activator | polymer | 253 | 28460.4 | 2 | UniProt (Q5SWW9) Pfam (PF00089) UniProt (by SIFTS) (P00749) | Homo sapiens (human) | U-plasminogen activator, uPA, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A, Urokinase-type plasminogen activator chain B |
| 3 | E, F (B, D) | 2-[(6-{[3'-(aminomethyl)biphenyl-3-yl]oxy}-4-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]-3,5-difluoropyridin-2-yl)oxy]-4-(dimethylamino)benzoic acid | non-polymer | 603.7 | 2 | Chemie (438) | |||
| 4 | G (D) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | H, I, J (B, C, D) | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62337.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1302.3 | |
| All* | Total formula weight | 63639.5 |
