3IE5
Crystal structure of Hyp-1 protein from Hypericum perforatum (St John's wort) involved in hypericin biosynthesis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phenolic oxidative coupling protein Hyp-1 | polymer | 165 | 18495.1 | 2 | UniProt (Q8H1L1) Pfam (PF00407) | Hypericum perforatum (St. John's wort) | |
| 2 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | D (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 4 | E, G, H, J, M (A, B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 5 | Chemie (PG4) | |||
| 5 | F (A) | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL | non-polymer | 370.4 | 1 | Chemie (PE8) | |||
| 6 | I, L (B) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
| 7 | K (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 8 | N, O (A, B) | water | water | 18.0 | 258 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 159 (UniProt: Q8H1L1)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ile -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Thr -1 | - | expression tag |
| Ile 14 | Thr 14 | SEE REMARK 999 |
| Leu 86 | Ile 86 | SEE REMARK 999 |
| Thr 119 | Ser 119 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36990.2 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2109.9 | |
| All* | Total formula weight | 39100.1 |
