3ICU

Protease-associated domain of the E3 ligase grail

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	E3 ubiquitin-protein ligase RNF128	polymer	194	21051.7	1	UniProt (Q8TEB7) Pfam (PF02225)	Homo sapiens (human)	RING finger protein 128, Gene related to energy in lymphocytes protein
2	B (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
3	C (A)	water	water		18.0	142	Chemie (HOH)

Sequence modifications

A: 38 - 204 (UniProt: Q8TEB7)

PDB	External Database	Details
Ala 11	-	expression tag
Ala 12	-	expression tag
Pro 13	-	expression tag
Glu 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
His 20	-	expression tag
Asp 21	-	expression tag
Tyr 22	-	expression tag
Asp 23	-	expression tag
Ile 24	-	expression tag
Pro 25	-	expression tag
Thr 26	-	expression tag
Thr 27	-	expression tag
Glu 28	-	expression tag
Asn 29	-	expression tag
Leu 30	-	expression tag
Tyr 31	-	expression tag
Phe 32	-	expression tag
Gln 33	-	expression tag
Gly 34	-	expression tag
Ala 35	-	expression tag
Met 36	-	expression tag
Asp 37	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	21051.7
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	21273.0

*Water molecules are not included.