3IC0
Crystal Structure of liganded hemoglobin in complex with a potent antisickling agent, INN-298
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Hemoglobin subunit alpha | polymer | 141 | 15150.4 | 2 | UniProt (P69905) Pfam (PF00042) | Homo sapiens (human) | Hemoglobin alpha chain, Alpha-globin |
| 2 | B, D (B, D) | Hemoglobin subunit beta | polymer | 146 | 15890.2 | 2 | UniProt (P68871) Pfam (PF00042) | Homo sapiens (human) | Hemoglobin beta chain, Beta-globin, LVV-hemorphin-7 |
| 3 | E, I, K, P (A, B, C, D) | OXYGEN MOLECULE | non-polymer | 32.0 | 4 | Chemie (OXY) | |||
| 4 | F, J, L, Q (A, B, C, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 5 | G, H, M, N (A, C) | 2-[(2-methoxy-5-methylphenoxy)methyl]pyridine | non-polymer | 229.3 | 4 | Chemie (B77) | |||
| 6 | O, R (C, D) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 7 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 415 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62081.1 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3703.2 | |
| All* | Total formula weight | 65784.3 |
