3IB0
Structural basis of the prevention of NSAID-induced damage of the gastrointestinal tract by C-terminal half (C-lobe) of bovine colostrum protein lactoferrin: Binding and structural studies of C-lobe complex with diclofenac
Replaces: 2B6DReplaces: 3HWVEntity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Lactotransferrin | polymer | 345 | 37655.5 | 1 | UniProt (P24627) Pfam (PF00405) In PDB | Bos taurus (Bovine) | Lactoferrin, Lactoferricin-B, Lfcin-B |
2 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
3 | C | alpha-D-mannopyranose-(1-4)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G42402GU) | |||
4 | D | alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G62783KT) | |||
5 | A | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
6 | A | CARBONATE ION | non-polymer | 60.0 | 1 | Chemie (CO3) | |||
7 | A | 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID | non-polymer | 296.1 | 1 | Chemie (DIF) | |||
8 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
9 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
10 | A | ETHANOL | non-polymer | 46.1 | 1 | Chemie (EOH) | |||
11 | water | water | 18.0 | 509 | Chemie (HOH) |
Sequence modifications
A: 342 - 686 (UniProt: P24627)
PDB | External Database | Details |
---|---|---|
Lys 565 | Asn 584 | SEE SEQUENCE DETAILS |
Glu 608 | Lys 627 | SEE SEQUENCE DETAILS |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 37655.5 | |
Branched | Number of molecules | 3 |
Total formula weight | 2408.2 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 781.0 | |
All* | Total formula weight | 40844.7 |