3IAK
Crystal structure of human phosphodiesterase 4d (PDE4d) with papaverine.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 349 | 40096.4 | 1 | UniProt (Q08499) Pfam (PF00233) | Homo sapiens (human) | DPDE3, PDE43 |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | 1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXYISOQUINOLINE | non-polymer | 339.4 | 1 | Chemie (EV1) | |||
| 5 | E (A) | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
A: 86 - 413 (UniProt: Q08499)
| PDB | External Database | Details |
|---|---|---|
| Met 65 | - | expression tag |
| Gly 66 | - | expression tag |
| Ser 67 | - | expression tag |
| Ser 68 | - | expression tag |
| His 69 | - | expression tag |
| His 70 | - | expression tag |
| His 71 | - | expression tag |
| His 72 | - | expression tag |
| His 73 | - | expression tag |
| His 74 | - | expression tag |
| Ser 75 | - | expression tag |
| Ser 76 | - | expression tag |
| Gly 77 | - | expression tag |
| Leu 78 | - | expression tag |
| Val 79 | - | expression tag |
| Pro 80 | - | expression tag |
| Arg 81 | - | expression tag |
| Gly 82 | - | expression tag |
| Ser 83 | - | expression tag |
| His 84 | - | expression tag |
| Met 85 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40096.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 429.1 | |
| All* | Total formula weight | 40525.5 |
