3I7Z
Protein Tyrosine Phosphatase 1B - Transition state analog for the first catalytic step
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 321 | 37365.6 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase 1B, PTP-1B |
| 2 | B (B) | EGFR receptor fragment | polymer | 6 | 724.7 | 1 | Homo sapiens | ||
| 3 | C (A) | VANADATE ION | non-polymer | 114.9 | 1 | Chemie (VO4) | |||
| 4 | D, G (A, B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 5 | E, F (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38090.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 543.4 | |
| All* | Total formula weight | 38633.8 |
