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3I7Z

Protein Tyrosine Phosphatase 1B - Transition state analog for the first catalytic step

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase non-receptor type 1polymer32137365.61UniProt (P18031)
Pfam (PF00102)
Homo sapiens (human)Protein-tyrosine phosphatase 1B, PTP-1B
2B
(B)
EGFR receptor fragmentpolymer6724.71Homo sapiens
3C
(A)
VANADATE IONnon-polymer114.91Chemie (VO4)
PubChem (61672)
4D, G
(A, B)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.12Chemie (TRS)
PubChem (3777159)
5E, F
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
PubChem (753)
6H, I
(A, B)
waterwater18.0150Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight38090.4
Non-Polymers*Number of molecules5
Total formula weight543.4
All*Total formula weight38633.8
*Water molecules are not included.

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PDB entries from 2026-05-27

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