3I6A
Human GST A1-1 GIMF mutant with Glutathione
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Glutathione S-transferase A1 | polymer | 222 | 25703.1 | 8 | UniProt (P08263) Pfam (PF02798) Pfam (PF00043) | Homo sapiens (human) | GTH1, HA subunit 1, GST-epsilon, GSTA1-1, GST class-alpha member 1 |
| 2 | I, J, K, L, M... (A, B, C, D, E...) | GLUTATHIONE | non-polymer | 307.3 | 8 | Chemie (GSH) | |||
| 3 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 553 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 222 (UniProt: P08263)
| PDB | External Database | Details |
|---|---|---|
| Gly 12 | Ala 12 | engineered mutation |
| Ile 107 | Leu 107 | engineered mutation |
| Met 108 | Leu 108 | engineered mutation |
| Phe 111 | Val 111 | engineered mutation |
| Pro 208 | Met 208 | engineered mutation |
| Ile 211 | Lys 211 | engineered mutation |
| Tyr 212 | Ser 212 | engineered mutation |
| Val 213 | Leu 213 | engineered mutation |
| Arg 214 | Glu 214 | engineered mutation |
| Thr 215 | Glu 215 | engineered mutation |
| Val 216 | Ala 216 | engineered mutation |
| Tyr 217 | Arg 217 | engineered mutation |
| Asn 218 | Lys 218 | engineered mutation |
| Pro 222 | Phe 222 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 205624.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2458.6 | |
| All* | Total formula weight | 208083.5 |
