3I2T
Crystal structure of the unliganded Drosophila Epidermal Growth Factor Receptor ectodomain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor, isoform A | polymer | 551 | 62451.7 | 1 | UniProt (Q8MLW0) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) UniProt (by SIFTS) (P04412) | Drosophila melanogaster (Fruit fly) | |
| 2 | B (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G05026ZL) | |||
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D, E (D, E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 5 | F (F) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G09988GX) | |||
| 6 | G (A) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A: 1 - 545 (UniProt: Q8MLW0)
| PDB | External Database | Details |
|---|---|---|
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ile 2 | Val 52 | SEE REMARK 999 |
| Asn 493 | Thr 543 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 62451.7 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2608.4 | |
| All* | Total formula weight | 65060.2 |
