3I0S
crystal structure of HIV reverse transcriptase in complex with inhibitor 7
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Reverse transcriptase/ribonuclease H | polymer | 563 | 64895.3 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) In PDB | HIV-1 M:B_HXB2R (HIV-1) | Pr160Gag-Pol, Matrix protein p17, MA, Capsid protein p24, CA, Spacer peptide p2, Nucleocapsid protein p7, NC, Transframe peptide, TF, p6-pol, p6*, Protease, Retropepsin, PR, Reverse transcriptase/ribonuclease H, p66 RT, p51 RT, p15, Integrase, IN |
2 | B | p51 RT | polymer | 443 | 51731.4 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) In PDB | HIV-1 M:B_HXB2R (HIV-1) | Pr160Gag-Pol, Matrix protein p17, MA, Capsid protein p24, CA, Spacer peptide p2, Nucleocapsid protein p7, NC, Transframe peptide, TF, p6-pol, p6*, Protease, Retropepsin, PR, Reverse transcriptase/ribonuclease H, p66 RT, p51 RT, p15, Integrase, IN |
3 | A | S-{2-[(2-chloro-4-sulfamoylphenyl)amino]-2-oxoethyl} 6,8-dichloro-3,4-dihydroquinoline-1(2H)-carbothioate | non-polymer | 508.8 | 1 | Chemie (RT7) |
Sequence modifications
A: 1 - 560 (UniProt: P04585)
B: 1 - 440 (UniProt: P04585)
PDB | External Database | Details |
---|---|---|
Met -2 | - | expression tag |
Asn -1 | - | expression tag |
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met -2 | - | expression tag |
Asn -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 116626.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 508.8 | |
All* | Total formula weight | 117135.6 |