3HY3
Structure of human MTHFS with 10-formyltetrahydrofolate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 5-formyltetrahydrofolate cyclo-ligase | polymer | 203 | 23289.7 | 1 | UniProt (P49914) Pfam (PF01812) | Homo sapiens (human) | 5,10-methenyl-tetrahydrofolate synthetase, Methenyl-THF synthetase, MTHFS |
| 2 | B (A) | N-({4-[{[(2R,4S,4aR,6S,8aS)-2-amino-4-hydroxydecahydropteridin-6-yl]methyl}(formyl)amino]phenyl}carbonyl)-D-glutamic acid | non-polymer | 479.5 | 1 | Chemie (10F) | |||
| 3 | C, D (A) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 4 | E, F, G, H, I... (A) | MAGNESIUM ION | non-polymer | 24.3 | 9 | Chemie (MG) | |||
| 5 | N (A) | water | water | 18.0 | 137 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23289.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 815.6 | |
| All* | Total formula weight | 24105.3 |
