3HY1
Crystal Structure of catalytic fragment of E. coli AlaRS G237A in complex with SerSA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alanyl-tRNA synthetase | polymer | 441 | 49938.1 | 2 | UniProt (P00957) Pfam (PF01411) | Escherichia coli | Alanine-tRNA ligase, AlaRS |
| 2 | C (A) | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE | non-polymer | 433.4 | 1 | Chemie (SSA) | |||
| 3 | D (A) | 2-HYDROXYETHYL DISULFIDE | non-polymer | 154.3 | 1 | Chemie (HED) | |||
| 4 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | F (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | G (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 7 | H, I (A, B) | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 441 (UniProt: P00957)
| PDB | External Database | Details |
|---|---|---|
| Leu 104 | His 105 | engineered mutation |
| Leu 108 | Gln 109 | engineered mutation |
| Leu 112 | Glu 113 | engineered mutation |
| Ala 237 | Gly 238 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 99876.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 903.3 | |
| All* | Total formula weight | 100779.4 |
