3HXU
Crystal Structure of catalytic fragment of E. coli AlaRS in complex with AlaSA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Alanyl-tRNA synthetase | polymer | 441 | 49924.1 | 1 | UniProt (P00957) Pfam (PF01411) In PDB | Escherichia coli | Alanine-tRNA ligase, AlaRS |
| 2 | A | '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE | non-polymer | 417.4 | 1 | Chemie (A5A) | |||
| 3 | A | 2-HYDROXYETHYL DISULFIDE | non-polymer | 154.3 | 1 | Chemie (HED) | |||
| 4 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 5 | A | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
| 6 | water | water | 18.0 | 631 | Chemie (HOH) |
Sequence modifications
A: 1 - 441 (UniProt: P00957)
| PDB | External Database | Details |
|---|---|---|
| Leu 104 | His 105 | engineered mutation |
| Leu 108 | Gln 109 | engineered mutation |
| Leu 112 | Glu 113 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49924.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 966.2 | |
| All* | Total formula weight | 50890.3 |
