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3HXT

Structure of human MTHFS

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
5-formyltetrahydrofolate cyclo-ligasepolymer20323289.71UniProt (P49914)
Pfam (PF01812)
Homo sapiens (human)5,10-methenyl-tetrahydrofolate synthetase, Methenyl-THF synthetase, MTHFS
2B, C, E, G
(A)
NICKEL (II) IONnon-polymer58.74Chemie (NI)
3D, F, H, I, J...
(A)
MAGNESIUM IONnon-polymer24.37Chemie (MG)
4M
(A)
waterwater18.0156Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23289.7
Non-Polymers*Number of molecules11
Total formula weight404.9
All*Total formula weight23694.6
*Water molecules are not included.

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PDB entries from 2025-06-25

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