3HX9

Structure of heme-degrader, MhuD (Rv3592), from Mycobacterium tuberculosis with two hemes bound in its active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protein Rv3592	polymer	124	13249.9	2	UniProt (O06156) Pfam (PF03992) UniProt (by SIFTS) (P9WKH3)	Mycobacterium tuberculosis
2	C, E, F, H (A, B)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	4	Chemie (HEM)
3	D, G (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	I, J (A, B)	water	water		18.0	123	Chemie (HOH)

Sequence modifications

A, B: 1 - 105 (UniProt: O06156)

PDB	External Database	Details
Gly 106	-	expression tag
Gly 107	-	expression tag
Val 108	-	expression tag
Pro 109	-	expression tag
Arg 110	-	expression tag
Gly 111	-	expression tag
Lys 112	-	expression tag
Leu 113	-	expression tag
Ala 114	-	expression tag
Ala 115	-	expression tag
Ala 116	-	expression tag
Leu 117	-	expression tag
Glu 118	-	expression tag
His 119	-	expression tag
His 120	-	expression tag
His 121	-	expression tag
His 122	-	expression tag
His 123	-	expression tag
His 124	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	26499.9
Non-Polymers*	Number of molecules	6
	Total formula weight	2536.9
All*	Total formula weight	29036.7

*Water molecules are not included.