3HWK

Crystal structure of methylcitrate synthase from Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Methylcitrate synthase	polymer	414	45311.9	8	UniProt (O08395) Pfam (PF00285) UniProt (by SIFTS) (I6Y9Q3)	Mycobacterium tuberculosis	CITRATE SYNTHASE I GLTA1
2	I, J, K, L, M... (A, B, C, D, E...)	SUCCINIC ACID	non-polymer		118.1	16	Chemie (SIN)
3	AA, BA, CA, DA, EA... (C, D, E, F, G...)	water	water		18.0	960	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 393 (UniProt: O08395)

PDB	External Database	Details
Met -20	-	expression tag
Ala -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Met -12	-	expression tag
Gly -11	-	expression tag
Thr -10	-	expression tag
Leu -9	-	expression tag
Glu -8	-	expression tag
Ala -7	-	expression tag
Gln -6	-	expression tag
Thr -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	362495.2
Non-Polymers*	Number of molecules	16
	Total formula weight	1889.4
All*	Total formula weight	364384.6

*Water molecules are not included.