3HWD
Crystal structure of Siderocalin (NGAL, Lipocalin 2) K125A-K134A mutant complexed with Ferric Enterobactin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Neutrophil gelatinase-associated lipocalin | polymer | 198 | 22481.8 | 3 | UniProt (P80188) Pfam (PF00061) | Homo sapiens (human) | NGAL, p25, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3 |
| 2 | D, E, F, G, H... (A, C) | SODIUM ION | non-polymer | 23.0 | 7 | Chemie (NA) | |||
| 3 | K, L, M (A, B, C) | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence modifications
A, B, C: -19 - 178 (UniProt: P80188)
| PDB | External Database | Details |
|---|---|---|
| Ser 87 | Cys 107 | engineered mutation |
| Ala 125 | Lys 145 | engineered mutation |
| Ala 134 | Lys 154 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 67445.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 160.9 | |
| All* | Total formula weight | 67606.2 |
