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3HVC

Crystal structure of human p38alpha MAP kinase

Replaces:  2P5A
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mitogen-activated protein kinase 14polymer36241497.41UniProt (Q16539)
Pfam (PF00069)
Homo sapiens (human)Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A
2B, C
(A)
4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINEnon-polymer239.22Chemie (GG5)
3D
(A)
waterwater18.0193Chemie (HOH)
Sequence modifications
A: 1 - 360 (UniProt: Q16539)
PDBExternal DatabaseDetails
Gly -1-expression tag
Pro 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41497.4
Non-Polymers*Number of molecules2
Total formula weight478.5
All*Total formula weight41975.9
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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