3HUQ
Thieno[3,2-b]thiophene in complex with T4 lysozyme L99A/M102Q
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysozyme | polymer | 162 | 18419.1 | 1 | UniProt (P00720) Pfam (PF00959) | Enterobacteria phage T4 (Bacteriophage T4) | Lysis protein, Muramidase, Endolysin |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C (A) | thieno[3,2-b]thiophene | non-polymer | 140.2 | 1 | Chemie (J1Z) | |||
| 4 | D, E, F (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 3 | Chemie (BME) | |||
| 5 | G (A) | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence modifications
A: 1 - 162 (UniProt: P00720)
| PDB | External Database | Details |
|---|---|---|
| Asp 38 | Ser 38 | engineered mutation |
| Ala 99 | Leu 99 | engineered mutation |
| Gln 102 | Met 102 | engineered mutation |
| Asp 144 | Asn 144 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18419.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 469.6 | |
| All* | Total formula weight | 18888.7 |
