3HUJ
Crystal structure of human CD1d-alpha-Galactosylceramide in complex with semi-invariant NKT cell receptor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | T-cell surface glycoprotein CD1d | polymer | 284 | 32324.4 | 2 | UniProt (P15813) Pfam (PF16497) Pfam (PF07654) In PDB | Homo sapiens (human) | R3G1 |
2 | B, D | Beta-2-microglobulin | polymer | 99 | 11748.2 | 2 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
3 | E, G | NKT15 T cell receptor alpha-chain | polymer | 209 | 23227.7 | 2 | Homo sapiens (human) | ||
4 | F, H | NKT15 T cell receptor beta-chain | polymer | 246 | 28033.2 | 2 | Homo sapiens (human) | ||
5 | I | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 383.3 | 1 | In PDB GlyTouCan (G90333CG) | |||
6 | J | beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G31883CF) | |||
7 | A, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
8 | A, C | N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE | non-polymer | 858.3 | 2 | Chemie (AGH) | |||
9 | H | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
10 | water | water | 18.0 | 482 | Chemie (HOH) |
Sequence modifications
A, C: 3 - 277 (UniProt: P15813)
PDB | External Database | Details |
---|---|---|
Ser 0 | - | expression tag |
Pro 1 | - | expression tag |
Gly 2 | - | expression tag |
His 278 | - | expression tag |
His 279 | - | expression tag |
His 280 | - | expression tag |
His 281 | - | expression tag |
His 282 | - | expression tag |
His 283 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 190666.8 | |
Branched | Number of molecules | 2 |
Total formula weight | 969.9 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 2183.4 | |
All* | Total formula weight | 193820.0 |