3HTH

Crystal structure of multidrug binding protein EbrR complexed with proflavin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	EbrA repressor	polymer	217	23266.3	3	UniProt (Q79SH7) Pfam (PF00440) Pfam (PF17940)	Streptomyces lividans
2	D, E, H (A, C)	NICKEL (II) ION	non-polymer		58.7	3	Chemie (NI)
3	F, G (A, B)	PROFLAVIN	non-polymer		209.2	2	Chemie (PRL)
4	I, J, K (A, B, C)	water	water		18.0	81	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 197 (UniProt: Q79SH7)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	69798.8
Non-Polymers*	Number of molecules	5
	Total formula weight	594.6
All*	Total formula weight	70393.4

*Water molecules are not included.