3HRC
Crystal structure of a mutant of human PDK1 Kinase domain in complex with ATP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 3-phosphoinositide-dependent protein kinase 1 | polymer | 311 | 35392.6 | 1 | UniProt (O15530) Pfam (PF00069) In PDB | Homo sapiens (human) | hPDK1 |
2 | A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
3 | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
A: 51 - 359 (UniProt: O15530)
PDB | External Database | Details |
---|---|---|
Gly 49 | - | SEE REMARK 999 |
Ala 50 | - | SEE REMARK 999 |
Gly 288 | Tyr 288 | engineered mutation |
Ala 292 | Gln 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35392.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 507.2 | |
All* | Total formula weight | 35899.7 |