3HP9

Crystal structure of SSB/Exonuclease I in complex with inhibitor CFAM

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Exodeoxyribonuclease I	polymer	482	55510.6	1	UniProt (P04995) Pfam (PF00929) Pfam (PF08411) In PDB	Escherichia coli	Exonuclease I, DNA deoxyribophosphodiesterase, dRPase
2	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	A	2-{[2-chloro-5-(trifluoromethyl)phenyl]amino}-5-methoxybenzoic acid	non-polymer		345.7	1	Chemie (CF1)
4	A	DIMETHYL SULFOXIDE	non-polymer		78.1	5	Chemie (DMS)
5	A	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
6		water	water		18.0	448	Chemie (HOH)

Sequence modifications

A: 1 - 475 (UniProt: P04995)

PDB	External Database	Details
Asp 472	Glu 472	conflict
Glu 476	-	expression tag
His 477	-	expression tag
His 478	-	expression tag
His 479	-	expression tag
His 480	-	expression tag
His 481	-	expression tag
His 482	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	55510.6
Non-Polymers*	Number of molecules	8
	Total formula weight	822.7
All*	Total formula weight	56333.3

*Water molecules are not included.