3HOU

Complete RNA polymerase II elongation complex I with a T-U mismatch

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, P (A, M)	DNA-directed RNA polymerase II subunit RPB1	polymer	1733	191821.6	2	UniProt (P04050) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990)	Saccharomyces cerevisiae (Baker's yeast)	RNA polymerase II subunit B1, RNA polymerase II subunit 1, DNA-directed RNA polymerase III largest subunit, RNA polymerase II subunit B220
2	B, Q (B, N)	DNA-directed RNA polymerase II subunit RPB2	polymer	1224	138937.3	2	UniProt (P08518) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560)	Saccharomyces cerevisiae (Baker's yeast)	RNA polymerase II subunit 2, DNA-directed RNA polymerase II 140 kDa polypeptide, B150
3	C, R (C, O)	DNA-directed RNA polymerase II subunit RPB3	polymer	318	35330.5	2	UniProt (P16370) Pfam (PF01193) Pfam (PF01000)	Saccharomyces cerevisiae (Baker's yeast)	RNA polymerase II subunit B3, RNA polymerase II subunit 3, DNA-directed RNA polymerase II 45 kDa polypeptide, B44.5
4	D, S (D, P)	DNA-directed RNA polymerase II subunit RPB4	polymer	221	25451.2	2	UniProt (P20433) Pfam (PF03874)	Saccharomyces cerevisiae (Baker's yeast)	RNA polymerase II subunit B4, DNA-directed RNA polymerase II 32 kDa polypeptide, B32
5	E, T (E, Q)	DNA-directed RNA polymerases I, II, and III subunit RPABC1	polymer	215	25117.1	2	UniProt (P20434) Pfam (PF03871) Pfam (PF01191)	Saccharomyces cerevisiae (Baker's yeast)	RNA polymerases I, II, and III subunit ABC1, DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide, ABC27
6	F, U (F, R)	DNA-directed RNA polymerases I, II, and III subunit RPABC2	polymer	155	17931.8	2	UniProt (P20435) Pfam (PF01192)	Saccharomyces cerevisiae (Baker's yeast)	RNA polymerases I, II, and III subunit ABC2, DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide, ABC23
7	G, V (G, S)	DNA-directed RNA polymerase II subunit RPB7	polymer	171	19081.1	2	UniProt (P34087) Pfam (PF03876) Pfam (PF00575)	Saccharomyces cerevisiae (Baker's yeast)	RNA polymerase II subunit B7, B16
8	H, W (H, T)	DNA-directed RNA polymerases I, II, and III subunit RPABC3	polymer	146	16525.4	2	UniProt (P20436) Pfam (PF03870)	Saccharomyces cerevisiae (Baker's yeast)	RNA polymerases I, II, and III subunit ABC3, DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide, ABC14.5, ABC14.4
9	I, X (I, U)	DNA-directed RNA polymerase II subunit RPB9	polymer	122	14308.2	2	UniProt (P27999) Pfam (PF02150) Pfam (PF01096)	Saccharomyces cerevisiae (Baker's yeast)	RNA polymerase II subunit B9, DNA-directed RNA polymerase II subunit 9, DNA-directed RNA polymerase II 14.2 kDa polypeptide, B12.6
10	J, Y (J, V)	DNA-directed RNA polymerases I, II, and III subunit RPABC5	polymer	70	8290.7	2	UniProt (P22139) Pfam (PF01194)	Saccharomyces cerevisiae (Baker's yeast)	RNA polymerases I, II, and III subunit ABC5, DNA-directed RNA polymerases I, II, and III 8.3 kDa polypeptide, ABC10-beta, ABC8
11	K, Z (K, W)	DNA-directed RNA polymerase II subunit RPB11	polymer	120	13633.5	2	UniProt (P38902) Pfam (PF13656)	Saccharomyces cerevisiae (Baker's yeast)	RNA polymerase II subunit B11, DNA-directed RNA polymerase II 13.6 kDa polypeptide, B13.6
12	AA, L (L, X)	DNA-directed RNA polymerases I, II, and III subunit RPABC4	polymer	70	7730.0	2	UniProt (P40422) Pfam (PF03604)	Saccharomyces cerevisiae (Baker's yeast)	RNA polymerases I, II, and III subunit ABC4, ABC10-alpha
13	BA, M (1, 4)	5'-D(*AP*GP*CP*TP*CP*A*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3'	polymer	26	8058.0	2			TEMPLATE DNA
14	CA, N (2, 5)	5'-D(*A*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3'	polymer	13	3950.6	2			NONTEMPLATE DNA
15	DA, O (3, 6)	5'-R(*UP*GP*CP*AP*UP*U*UP*CP*GP*AP*CP*CP*AP*GP*GP*CP*U)-3'	polymer	17	5380.2	2			PRODUCT RNA
16	EA, FA, GA, HA, IA... (A, B, C, I, J...)	ZINC ION	non-polymer		65.4	16	Chemie (ZN)

Contents of the asymmetric unit

Polymers	Number of chains	30
	Total formula weight	1063094.1
Non-Polymers*	Number of molecules	16
	Total formula weight	1046.5
All*	Total formula weight	1064140.7

*Water molecules are not included.