3HOK

X-ray Crystal Structure of Human Heme Oxygenase-1 with (2R, 4S)-2-[2-(4-Chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-4[((5-trifluoromethylpyridin-2-yl)thio)methyl]-1,3-dioxolane: A Novel, Inducible Binding Mode

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heme oxygenase 1	polymer	233	26898.6	2	UniProt (P09601) Pfam (PF01126)	Homo sapiens (human)	HO-1
2	C, D (A, B)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	E (B)	2-({[(2R,4S)-2-[2-(4-chlorophenyl)ethyl]-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl}sulfanyl)-5-(trifluoromethyl)pyridine	non-polymer		483.9	1	Chemie (Q80)
4	F, G (A, B)	water	water		18.0	186	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53797.2
Non-Polymers*	Number of molecules	3
	Total formula weight	1716.9
All*	Total formula weight	55514.1

*Water molecules are not included.