3HOK
X-ray Crystal Structure of Human Heme Oxygenase-1 with (2R, 4S)-2-[2-(4-Chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-4[((5-trifluoromethylpyridin-2-yl)thio)methyl]-1,3-dioxolane: A Novel, Inducible Binding Mode
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Heme oxygenase 1 | polymer | 233 | 26898.6 | 2 | UniProt (P09601) Pfam (PF01126) In PDB | Homo sapiens (human) | HO-1 |
| 2 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | B | 2-({[(2R,4S)-2-[2-(4-chlorophenyl)ethyl]-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl}sulfanyl)-5-(trifluoromethyl)pyridine | non-polymer | 483.9 | 1 | Chemie (Q80) | |||
| 4 | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53797.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1716.9 | |
| All* | Total formula weight | 55514.1 |
