3HND
Crystal structure of human ribonucleotide reductase 1 bound to the effector TTP and substrate GDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ribonucleoside-diphosphate reductase large subunit | polymer | 792 | 90179.0 | 2 | UniProt (P23921) Pfam (PF03477) Pfam (PF00317) Pfam (PF02867) | Homo sapiens (human) | Ribonucleoside-diphosphate reductase subunit M1, Ribonucleotide reductase large subunit |
| 2 | C, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 3 | D, J (A, B) | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 2 | Chemie (TTP) | |||
| 4 | E, K (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 5 | F, G, H, L (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 180358.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2283.6 | |
| All* | Total formula weight | 182641.6 |
