3HL5
Crystal structure of XIAP BIR3 with CS3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Baculoviral IAP repeat-containing protein 4 | polymer | 95 | 10980.3 | 2 | UniProt (P98170) Pfam (PF00653) | Homo sapiens (human) | E3 ubiquitin-protein ligase XIAP, Inhibitor of apoptosis protein 3, X-linked inhibitor of apoptosis protein, X-linked IAP, IAP-like protein, HILP |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | (3S)-1-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-3-methyl-N-(2-pyrimidin-2-ylphenyl)-L-prolinamide | non-polymer | 506.6 | 2 | Chemie (9JZ) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A, B: 256 - 346 (UniProt: P98170)
| PDB | External Database | Details |
|---|---|---|
| Gly 252 | - | expression tag |
| Ser 253 | - | expression tag |
| His 254 | - | expression tag |
| Met 255 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21960.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1144.1 | |
| All* | Total formula weight | 23104.8 |
