3HK3
Crystal structure of murine thrombin mutant W215A/E217A (one molecule in the asymmetric unit)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thrombin light chain | polymer | 44 | 5105.7 | 1 | UniProt (P19221) Pfam (PF09396) | Mus musculus (mouse) | Coagulation factor II |
| 2 | B (B) | Thrombin heavy chain | polymer | 258 | 29795.5 | 1 | UniProt (P19221) Pfam (PF00089) | Mus musculus (mouse) | Coagulation factor II |
| 3 | C, D (A, B) | water | water | 18.0 | 240 | Chemie (HOH) |
Sequence modifications
B: 16 - 246 (UniProt: P19221)
| PDB | External Database | Details |
|---|---|---|
| Ala 215 | Trp 587 | engineered mutation |
| Ala 217 | Glu 589 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34901.2 | |
| All* | Total formula weight | 34901.2 |
