3HHD
Structure of the Human Fatty Acid Synthase KS-MAT Didomain as a Framework for Inhibitor Design.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Fatty acid synthase | polymer | 965 | 104477.2 | 4 | UniProt (P49327) Pfam (PF00109) Pfam (PF02801) Pfam (PF16197) Pfam (PF00698) Pfam (PF21089) In PDB | Homo sapiens (human) | [Acyl-carrier-protein] S-acetyltransferase, [Acyl-carrier-protein] S-malonyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase |
| 2 | C, D | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | water | water | 18.0 | 1808 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 963 (UniProt: P49327)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Thr 0 | - | expression tag |
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 417908.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 417979.6 |
