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3HEG

P38 in complex with Sorafenib

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mitogen-activated protein kinase 14polymer34839905.71UniProt (Q16539)
Pfam (PF00069)
Homo sapiens (human)Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A
2B
(A)
4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDEnon-polymer464.81Chemie (BAX)
3C
(A)
waterwater18.0109Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39905.7
Non-Polymers*Number of molecules1
Total formula weight464.8
All*Total formula weight40370.5
*Water molecules are not included.

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PDB entries from 2025-07-23

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