3HA7

Crystal structure of HMA (MMAA4) from mycobacterium tuberculosis complexed with S-adenosyl-N-decyl-aminoethyl (SADAE)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	METHOXY MYCOLIC ACID SYNTHASE 4	polymer	318	36521.3	1	UniProt (Q79FX8) Pfam (PF02353) In PDB	Mycobacterium tuberculosis	MMAA4 (METHYL MYCOLIC ACID SYNTHASE 4) (MMA4) (HYDROXY MYCOLIC ACID SYNTHASE)
2	A	5'-S-[2-(decylamino)ethyl]-5'-thioadenosine	non-polymer		466.6	1	Chemie (B32)
3		water	water		18.0	45	Chemie (HOH)

Sequence modifications

A: 4 - 301 (UniProt: Q79FX8)

PDB	External Database	Details
Met -16	-	expression tag
Gly -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
His -12	-	expression tag
Tyr -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Ser -6	-	expression tag
Ser -5	-	expression tag
Gly -4	-	expression tag
Leu -3	-	expression tag
Val -2	-	expression tag
Pro -1	-	expression tag
Arg 0	-	expression tag
Gly 1	-	expression tag
Ser 2	-	expression tag
His 3	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36521.3
Non-Polymers*	Number of molecules	1
	Total formula weight	466.6
All*	Total formula weight	36987.9

*Water molecules are not included.