3H9Y
Crystal structure of the IgE-Fc3-4 domains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E | Ig epsilon chain C region | polymer | 223 | 24920.1 | 3 | UniProt (P01854) Pfam (PF07654) In PDB | Homo sapiens (human) | |
| 2 | C | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G34442SS) | |||
| 3 | D, F | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 4 | E | AMMONIUM ION | non-polymer | 18.0 | 1 | Chemie (NH4) | |||
| 5 | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A, B, E: 328 - 547 (UniProt: P01854)
| PDB | External Database | Details |
|---|---|---|
| Ala 325 | - | expression tag |
| Asp 326 | - | expression tag |
| Pro 327 | - | expression tag |
| Gln 371 | Asn 252 | engineered mutation |
| Gln 383 | Asn 264 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 74760.4 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2894.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 18.0 | |
| All* | Total formula weight | 77673.1 |
