3H8D

Crystal structure of Myosin VI in complex with Dab2 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Myosin-VI	polymer	141	16412.8	4	UniProt (Q64331) Pfam (PF16521) In PDB	Mus musculus (mouse)
2	E, F, G, H	Disabled homolog 2	polymer	48	4994.1	4	UniProt (O88797) In PDB	Rattus norvegicus (Rat)	DOC-2, Mitogen-responsive phosphoprotein, C9
3	A, B, C	THIOCYANATE ION	non-polymer		58.1	3	Chemie (SCN)
4	C	2,3-DIHYDROXY-1,4-DITHIOBUTANE	non-polymer		154.3	1	Chemie (DTT)
5	H	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6		water	water		18.0	266	Chemie (HOH)

Sequence modifications

A, B, C, D: 1137 - 1265 (UniProt: Q64331)

PDB	External Database	Details
Gly 1135	-	expression tag
Ser 1136	-	expression tag
Gly 1266	-	expression tag
Ser 1267	-	expression tag
Ser 1268	-	expression tag
Gly 1269	-	expression tag
Gly 1270	-	expression tag
Ser 1271	-	expression tag
Leu 1272	-	expression tag
Val 1273	-	expression tag
Pro 1274	-	expression tag
Arg 1275	-	expression tag

E, F, G, H: 673 - 711 (UniProt: O88797)

PDB	External Database	Details
Gly 664	-	expression tag
Ser 665	-	expression tag
Ser 666	-	expression tag
Ser 667	-	expression tag
Gly 668	-	expression tag
Gly 669	-	expression tag
Gly 670	-	expression tag
Ser 671	-	expression tag
Ser 672	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	85627.7
Non-Polymers*	Number of molecules	5
	Total formula weight	364.0
All*	Total formula weight	85991.7

*Water molecules are not included.