3H6S
Structure of clitocypin - cathepsin V complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cathepsin L2 | polymer | 221 | 24087.1 | 4 | UniProt (O60911) Pfam (PF00112) | Homo sapiens (human) | Cathepsin V, Cathepsin U |
| 2 | E, F, G, H (E, F, G, H) | Clitocypin analog | polymer | 152 | 16914.7 | 4 | UniProt (Q3Y9I6) Pfam (PF10467) | Clitocybe nebularis (Clouded agaric) | |
| 3 | I, J, K, L, M... (A, B, C, D, F) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | O, P, Q, R, S... (A, B, C, D, E...) | water | water | 18.0 | 857 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 221 (UniProt: O60911)
E, F, G, H: 1 - 152 (UniProt: Q3Y9I6)
| PDB | External Database | Details |
|---|---|---|
| Gln 108 | Asn 221 | engineered mutation |
| Asp 179 | Asn 292 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Sme 82 | Leu 82 | engineered mutation |
| Sme 89 | Ile 89 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 164007.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 576.4 | |
| All* | Total formula weight | 164583.3 |
