3H59
Hepatitis C virus polymerase NS5B with thiazine inhibitor 2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | RNA-directed RNA polymerase | polymer | 576 | 64176.7 | 2 | UniProt (P26663) Pfam (PF00998) In PDB | Hepatitis C virus | NS5B, p68 |
2 | A, B | N-{3-[(5S)-5-(1,1-dimethylpropyl)-1-(4-fluoro-3-methylbenzyl)-4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]-1,1-dioxido-4H-1,4-benzothiazin-7-yl}methanesulfonamide | non-polymer | 563.7 | 2 | Chemie (H59) | |||
3 | water | water | 18.0 | 738 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 570 (UniProt: P26663)
PDB | External Database | Details |
---|---|---|
Met -5 | - | EXPRESSION TAG |
His -4 | - | EXPRESSION TAG |
His -3 | - | EXPRESSION TAG |
His -2 | - | EXPRESSION TAG |
His -1 | - | EXPRESSION TAG |
His 0 | - | EXPRESSION TAG |
His 1 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 128353.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1127.3 | |
All* | Total formula weight | 129480.6 |