3H3B
Crystal structure of the single-chain Fv (scFv) fragment of an anti-ErbB2 antibody chA21 in complex with residues 1-192 of ErbB2 extracellular domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Receptor tyrosine-protein kinase erbB-2 | polymer | 194 | 21669.6 | 2 | UniProt (P04626) Pfam (PF01030) | Homo sapiens (human) | p185erbB2, C-erbB-2, NEU proto-oncogene, Tyrosine kinase-type cell surface receptor HER2, MLN 19 |
| 2 | C, D (C, D) | anti-ErbB2 antibody chA21 | polymer | 259 | 27559.4 | 2 | Mus musculus (mouse) | ||
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 239 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 192 (UniProt: P04626)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 98458.1 | |
| All* | Total formula weight | 98458.1 |
