3GXT
Crystal structure of alpha-galactosidase A at pH 4.5 complexed with 1-deoxygalactonijirimycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alpha-galactosidase A | polymer | 398 | 45394.5 | 2 | UniProt (P06280) Pfam (PF16499) Pfam (PF17450) | Homo sapiens (Human) | Alpha-D-galactoside galactohydrolase, Alpha-D-galactosidase A, Melibiase |
| 2 | C, D, F (C, D, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 3 | E (E) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900112) GlyTouCan (G00891MP) | 3alpha-alpha-mannobiose | ||
| 4 | G (G) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G48068RF) | |||
| 5 | H (H) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 6 | I, J, K, N, O (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 7 | L, P (A, B) | 1-DEOXYNOJIRIMYCIN | non-polymer | 163.2 | 2 | Chemie (NOJ) PubChem (1374) PubChem (29435) PubChem (44387838) PubChem (72258) PubChem (46780624) PubChem (46783361) PubChem (58195791) PubChem (58241649) PubChem (58622819) PubChem (59892309) PubChem (59928089) PubChem (68012331) PubChem (68197421) PubChem (68197422) PubChem (68226300) PubChem (70254323) PubChem (452001) PubChem (89057096) PubChem (89288875) PubChem (90298233) PubChem (90298234) PubChem (176077) PubChem (5387598) PubChem (6603829) PubChem (6604844) PubChem (117948891) PubChem (118458168) PubChem (13018786) PubChem (10329607) PubChem (10352016) PubChem (10702150) PubChem (10888248) PubChem (11094965) PubChem (11105683) PubChem (11240664) PubChem (11957613) PubChem (13018788) PubChem (173365510) PubChem (173729950) PubChem (130756880) PubChem (131019201) PubChem (132769969) PubChem (133673282) PubChem (134694855) PubChem (159481540) PubChem (168093369) PubChem (173809871) PubChem (174403809) PubChem (175474820) | |||
| 8 | M (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 9 | Q, R (A, B) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90789.1 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 2950.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1027.9 | |
| All* | Total formula weight | 94767.7 |
