3GXT
Crystal structure of alpha-galactosidase A at pH 4.5 complexed with 1-deoxygalactonijirimycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alpha-galactosidase A | polymer | 398 | 45394.5 | 2 | UniProt (P06280) Pfam (PF16499) Pfam (PF17450) | Homo sapiens (Human) | Alpha-D-galactoside galactohydrolase, Alpha-D-galactosidase A, Melibiase |
| 2 | C, D, F (C, D, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 3 | E (E) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900112) GlyTouCan (G00891MP) | 3alpha-alpha-mannobiose | ||
| 4 | G (G) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G48068RF) | |||
| 5 | H (H) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 6 | I, J, K, N, O (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 7 | L, P (A, B) | 1-DEOXYNOJIRIMYCIN | non-polymer | 163.2 | 2 | Chemie (NOJ) | |||
| 8 | M (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 9 | Q, R (A, B) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90789.1 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 2950.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1027.9 | |
| All* | Total formula weight | 94767.7 |
