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3GSR

Crystal structure of the binary complex between HLA-A2 and HCMV NLV-M5V peptide variant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
HLA class I histocompatibility antigen, A-2 alpha chainpolymer27431753.11UniProt (P01892)
Pfam (PF00129)
Pfam (PF07654)
UniProt (by SIFTS) (P04439)
Homo sapiens (human)MHC class I antigen A*2
2B
(B)
Beta-2-microglobulinpolymer10011879.41UniProt (P61769)
Pfam (PF07654)
Homo sapiens (human)Beta-2-microglobulin form pI 5.3
3C
(P)
HCMV pp65 fragment 495-503, variant M5V (NLVPVVATV)polymer9911.11
4D, E, F
(A, B, P)
waterwater18.0175Chemie (HOH)
Sequence modifications
A: 1 - 274 (UniProt: P01892)
PDBExternal DatabaseDetails
Val 245Ala 269engineered mutation
B: 1 - 99 (UniProt: P61769)
PDBExternal DatabaseDetails
Met 0-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight44543.6
All*Total formula weight44543.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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