3GPS
Crystal structure of the F87M/L110M mutant of human transthyretin at pH 5.5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Transthyretin | polymer | 127 | 13779.4 | 4 | UniProt (P02766) Pfam (PF00576) In PDB | Homo sapiens (Human) | Prealbumin, TBPA, TTR, ATTR |
| 2 | D, A, B, C | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 3 | D, A, B, C | ACETATE ION | non-polymer | 59.0 | 10 | Chemie (ACT) | |||
| 4 | D, A, B, C | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 205 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 127 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Met 87 | Phe 107 | engineered mutation |
| Met 110 | Leu 130 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 55117.7 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 2020.0 | |
| All* | Total formula weight | 57137.7 |
