3GP0
Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 11 | polymer | 348 | 39752.3 | 1 | UniProt (Q15759) Pfam (PF00069) | Homo sapiens (human) | MAPK11, Mitogen-activated protein kinase p38 beta, MAP kinase p38 beta, p38b, p38-2, Stress-activated protein kinase 2 |
| 2 | B (A) | Nilotinib | non-polymer | 529.5 | 1 | Chemie (NIL) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A: 5 - 350 (UniProt: Q15759)
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | - | expression tag |
| Met 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39752.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 627.0 | |
| All* | Total formula weight | 40379.4 |
